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See the original image at telegraph.co.uk —

New pain relief is eight times stronger than morphine

telegraph.co.uk — A groundbreaking treatment for pain that is eight times stronger than morphine has been discovered by scientists. The revolutionary technique involves an injection that can combat serious discomfort for more than three days - 14 times as long as morphine.

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  • SidewinderX2, on 10/08/2008, -3/+77Is it also 8 time as addictive?
    • RodBorn, on 10/09/2008, -0/+29I have been using it now for a few hours and I don't feel a thiwwmkmkw.wmdkj837878798&(* gnoimllk,mio,u89ikd.....................
    • coheedcollapse, on 10/09/2008, -1/+25This quote:
      "appears to have few side effects and works by neutralising the chemical in the body that causes the brain to feel pain."

      Makes me think that it's not. Morphine works because it stimulates a part of your brain to create chemicals that lessen pain, this seems to neutralize the chemical that causes it in the first place. The fact that it actually neutralizes the chemicals secreted by cells when you're in pain furthers this because, don't quote me on this, but I don't think someone could be addicted to the neutralization of a chemical that is only created when they're in pain. I mean, if it's not in the bloodstream in normal circumstances, the drug shouldn't have much of an effect when a patient takes it when they're not hurting.

      I could be totally wrong though. I'm nowhere near a doctor.
      • isunktheship, on 10/09/2008, -0/+25Side effects may include: ***** AWESOME.
      • charlietuna, on 10/09/2008, -0/+1Pop-mech loves everything new. They are never unbiased.
      • Casserole69, on 10/09/2008, -0/+6Initially I would say it should be less addictive as well because of what you just said. But, because it neutralizes pain causing chemicals, the body may adapt by increasing the amount of chemicals it synthesizes for pain. Therefore hyperalgesia would probably be a side effect. If hyperalgesia is a side effect, then the person would probably not want to stop taking the drug.
    • fadetoone, on 10/09/2008, -3/+26Is it heroin? It's heroin, isn't it?
      • Elizle, on 10/09/2008, -3/+3Heroin is synthetic morphine.
      • whywait, on 10/09/2008, -3/+23ur synthetic morphine.
      • kcap122, on 10/09/2008, -0/+9Wrong. Heroin is chemically modified morphine. Specifically, acetylation at the two benzyl hydroxyl groups.
    • TrancePhreak, on 10/09/2008, -5/+4everything is addictive.
      • AThoughtOrTwo, on 10/14/2008, -0/+1Breathing is, so is eating, sleeping - a bunch of things.
    • DiggzDE, on 10/09/2008, -6/+3Marijuana?
    • kcap122, on 10/09/2008, -1/+5No, it's not. The method of action for most painkillers (besides the anti-inflammatories like advil, aspirin, etc) is to activate opiod receptors in the brain. Opiod agonist drugs cause temporary changes that make it harder for neurons to release the "pain signal,": PAP. They also cause the release of dopamine from the same neurons. As a result, you get two effects: diminished sensation, and pleasure. So when it wears off, the nerves overcompensate and can cause withdrawal effects, or compulsion to find more of the drug to continue the dopamine release.

      This new class of drugs doesn't enter or interact with nerves in any way. They block PAP from performing its job once it's released by binding to it, or competitively bind PAP receptors. I know that there is also some ongoing research into downregulation of PAP production, but I don't think that's come anywhere near legitimate yet.
      • kcap122, on 10/09/2008, -1/+1yah sorry correcting myself here, kept saying PAP after i read the article, but meant this thing i forgot the name of, "molecule P" or "factor P" or something

        edit: substance p. woot.
      • bobfell, on 10/09/2008, -1/+2This is not a new class of drugs, it is research into the basic cellular mechanisms of neurons in the brain. PAP is not a signaling molecule with receptors, it is an enzyme that converts a pain signaling molecule, AMP, into a pain suppressing molecule adenosine.

        That is why Mark says in the article he hopes to find a way to modify it for oral delivery. As is, it has to be injected with a needle right into the specific nerves that you want to inhibit.

        That would be like a nerve block which takes a skilled anesthesiologist to administer.
    • newms32, on 10/09/2008, -0/+2Short answer: No

      Long answer: Opiates produce pleasure by directly acting on mu opioid receptors on inhibitory neurons that project to an area of the brain called the ventral tegmental area (VTA). The VTA (along with the nearby nucleus accumbens) is responsible for the rewarding effects of many abused drugs such as amphetamine, cocaine and opiates. When the opioid receptors on these cells are activated, their firing is inhibited, but since they're inhibitory cells this results in an increase of activity in the VTA. This is perceived as pleasure and the resulting dopamine surge causes the behavior to be reinforced in subconscious memory in a way similar to how someone can learn so well about something they're excited about. Along with tons of other factors, this can lead to addiction.

      The treatment in the article works by getting rid of a chemical that causes pain (probably Substance P but I haven't looked it up). This bypasses the opioid system, so there won't be the reinforcing effects of opiates unless there's some weird roundabout mechanism that I don't know about.
    • bipolarruledout, on 10/09/2008, -0/+2Heroin was invented by Bayer in the first place because it was believed to be less addictive than morphine.
      • newms32, on 10/09/2008, -1/+2To be fair, it is damn good at getting rid of a cough.
      • snached, on 10/09/2008, -0/+1Yep. It used to be sold in those cute little Bayer glass bottles.
    • jeffsback2223, on 10/09/2008, -0/+1Could be 8 times as illegal as well D:
    • rakaur, on 10/10/2008, -0/+1Large animal tranquilizers are derived from fentanyl. Carfentanil is around 10,000 times the potency of morphine.
  • hnazareth16, on 10/08/2008, -1/+37This sounds like you pretty much won't feel anything at all -- an emo kid's dream.
    • FLarsen, on 10/09/2008, -0/+2But pain makes them feel alive?
    • Ashur420, on 10/09/2008, -0/+1This is all well and good but can I snort it?
  • flannerus, on 10/08/2008, -15/+3Cindy McCain's been on this ***** for six months, buried because it's old news, hehe.
  • Hetman, on 10/08/2008, -3/+84Damn I have seen so many stupid ass Palin articles on digg. When I read the title I thought it said "New Palin relief"
    • RgyaGramShad, on 10/09/2008, -3/+20I think we all need some Palin relief after seeing so much of that ***** on digg…
    • Hockey13, on 10/09/2008, -3/+3A few stories in the past few days have had the word "pain" in their titles. Every time I see that word on Digg, my mind reads "Palin." Strange.
    • nitsnipe, on 10/09/2008, -4/+2Same here, I almost expected something about Palin being 8 times stronger than McCain.
    • VitriolAndAngst, on 10/09/2008, -3/+2Well if it's Palin Relief -- I'll take three, please.
    • cloudberries, on 10/09/2008, -2/+7Well, I'll have a whole pack. And an extra shot of McNovocaine
  • SpectralSounds, on 10/08/2008, -2/+14I just to be prescribed fentanyl patches. Fentanyl is 81 times stronger than morphine. The patches lasted for 72 hours. So pain killing wise, I'm sure the patches are at least comparable to this new drug. But, I had some crazy ass side effects though. So, less side effects and less dependance would be a good thing if that what this new drug is capable of.

    Quiting and withdrawing from serious opiate addiction is no fun whatsoever.
    • SpectralSounds, on 10/08/2008, -0/+9Obviously all those drugs screwed with my head. I meant to type, "I used to be prescribed...." I'm losing my mind.
    • JoshuaGross, on 10/09/2008, -0/+2Holy... 81 times?
      In related news, I know a guy who has an overactive liver and the highest legal dose of morphine has no effect on him. I wonder if Fentanyl would work.
    • connieLingus, on 10/09/2008, -0/+3ahh yes the american way...do new drugs to get off old drugs.
      • secrity, on 10/09/2008, -0/+2It is not an opiate and there are people who cannot tolerate opiates.
    • FTG1, on 10/09/2008, -1/+1You can chew on those fentanyl patches and it ***** you up for ~8 hours. Depending on your dosage if it's 100 mcg you can stretch that 3 days out till at least a week ;)
    • shotgunefx, on 10/09/2008, -0/+1And the messed up thing is that for some cases, it still doesn't do enough.
    • elliotys, on 10/09/2008, -0/+1Lets not forget levorphanol. It's 100 x times as potent as morphine.
    • gahal, on 10/09/2008, -0/+1All I could think of was fentanyl when I read the headline. I have heard different figures of the potency, from 20x to 80x more potent (per mg) than pure heroin. Keep in mind that fentanyl is normally prescribed in micrograms and not milligrams like most pain killers.

      I had a friend that died from a massive OD of fentanyl when he cut open a 3-day patch and ate it. He was an idiot so it was only a matter of time.

      When I was young, I used to try lots of different drugs. I only ever injected once though. That night I thought I was trying morphine out of an opened patch. It turned out it was a fentanyl patch that someone had mistaken for a morphine patch. I thought I was dead. For days I was unable to even sit up for more than 30 seconds without starting to faint. It had my heart beating so softly that I was unable to even register a pulse. I could not feel my own heartbeat, and when I had people try to check my pulse they could not find one. I even had some friends try, two that were phlebotomists and one that was a nurse. Of course my heart was still beating, it was just beating so slow and softly that it was very hard to feel via touch.

      I have worked with a few people that were prescribed fentanyl lollipops. One of them had Multiple sclerosis, and the lollipops worked wonders for her. She would just suck on it till she was able to function and then would put it away. Far better than a patch, since they could stop ingesting the drug once they had enough.
  • NikoKun, on 10/08/2008, -7/+38I'm sure this will be greatly abused, and also have many horrible side effects...

    And yet meanwhile a relatively harmless pain reliever like Cannabis, is one of the most illegal drugs out there... -_-
    • madwaxer, on 10/08/2008, -1/+9The FDA █████ sucks!
      • quomen, on 10/09/2008, -0/+15I tried to reveal your spoiler but it won't work!

      • secrity, on 10/09/2008, -0/+1Just question marks
      • FLarsen, on 10/09/2008, -0/+1@secrity: Then you don't have the correct font. It's black boxes, forming a black rectangle when put together like that.
    • aznpwnzor, on 10/09/2008, -0/+9F*CK THE RIAA


      oh sry nvm
    • JDLamb88, on 10/09/2008, -8/+3THC is legal, you can get it in pill form. You just want to smoke weed, hippy.
      • kingmanic, on 10/09/2008, -1/+2Absorption rates differ greatly. Studies are on going.
      • elliotys, on 10/09/2008, -2/+2Actually Marinol, the pill form of THC has little to no efficacy. The marijuana plant has numerous active cannabinoids that have yet to be isolated, so smoking it, unfortunately for your lungs, is the only way to get any benefit from it.
      • gahal, on 10/09/2008, -0/+1Eating works better than smoking for chronic pain management. (that is of course for actual marijuana, not for Marinol). Just make sure it is heated first (cooked with food works for that part).

        Eating yields a slower absorption rate, and also a higher overall absorption. This causes less of an instant effect, but a more effective long-term one.

        And as a sidenote... Marinol is a joke. It fails on everything that real marijuana works on. Talk to anyone that has taken it.
    • OffPiste, on 10/09/2008, -6/+6***** Obama and his anti-weed campaign. Yeah he smoked when he was younger but now he wants to increase enforcement AND continue the current anti-hemp laws.
      • kevlar21, on 10/09/2008, -0/+3At least he won't raid medical patients. At least I think I remember him saying that…
      • wreckosaurus, on 10/09/2008, -0/+5Anti-weed campaign? Oh shut up, you got any other ***** stories you want to pull out of your ass. You're a right wing troll, and you're very transparent. I see you've recently shifted to trying to pretend to be an Obama supporter:

        Old offpiste: "Max this libtard out." "Barrack Hussein Obama. nuff said."

        New Offpiste (on the subject of veteran suicide): "Good!! They were probably going to vote for McLame. The overwhelming majority of active duty and vets vote Rethuglican. Less votes for McBush means fewer votes for Obama are needed for him to have a victory come November. Vote Change Vote Obama"
    • Hobbes24, on 10/09/2008, -5/+4ok maybe i just don't smoke enough weed to know, but how well does weed relieve pain? because i find it very hard to believe it does a better job than opiates

      also, my assumption is that if medical weed were legal, it wouldn't get prescribed for pain simply because it has the very potent and obvious side affect of, well, getting you stoned.

      now i know you can say you get high off of opiates too, but that's different, when your on painkillers all that really happens to you (usually) is that your in a good mood (i took medical painkillers for 6 months at one point).

      now compare that to getting high, getting high is a MUCH more drastic change in personality and consciousness i know withdrawal from weed is almost non-existent, and from opiates is can be a killer, but i still think they are better for pain

      and now, as i've talked in a slightly negative light about marijuana on digg, i shall prepare to be buried into oblivion
      • JaronDiggGuy, on 10/09/2008, -4/+4Buried for doing that *****, whiny, "I know I just spouted what I think is an unpopular opinion so I know I'll get dugg down now" *****.
      • Hobbes24, on 10/09/2008, -0/+3^ well maybe i wouldn't say that if it wasn't true 99% of the time
      • shotgunefx, on 10/09/2008, -1/+1As far as a pain killer, it's really not, it may help with muscular pain, and aches, but I don't think anyone is advocating giving you a joint for a broken bone, but it has plenty of beneficial side effects, against glaucoma, nausea control (chemo), anti-anxiety, and increasing of appetite for people who are failing to thrive (AIDs, cancers, etc). I don't think

        And no, opiates, especially if abused (which they are all the time) are hugely addictive. And I'll tell you right now, percs, etc can alter your mood just as much as grass. I suppose it depends on the person and the dosage, but I've seen people on percs and oxys doing the "heroin nod"
      • Hobbes24, on 10/09/2008, -2/+1-shotgun

        ...i said opiates are very addictive

        and i still think it's far easier to tell if a random person is on weed than painkillers, just the way they look, and more importantly the way they talk

        but then again that's just my own experiences, maybe i haven't been with enough people who have done tons of either
      • bobfell, on 10/09/2008, -1/+1I call *****, I was a stoner for years and I could go get high right in the middle of a shift and with a little visiene, no one had a clue. That includes taking tables of 10+ peoples orders without writing anything down.

        Painkillers... no can do! Well what are you talking about? NSAIDs? Opiates, no way.
      • yournightmare, on 10/09/2008, -1/+1bobfell, that's just your experience. I can function normally on high doses of opiates, but if I take one hit of low-grade ***** I'm totally worthless. Not everybody responds to the same drugs the same way you do.
  • johnoneal, on 10/09/2008, -0/+7I know a guy.....
  • BoonTobias, on 10/09/2008, -9/+1(finally) i just had a little bottle of absinthe man, this ***** is good
  • kangy3213, on 10/09/2008, -4/+5its a trap
  • KORGOTH, on 10/09/2008, -3/+4Sounds like fun...
  • Tophillious, on 10/09/2008, -2/+28Oh boy! Another breakthrough that we'll never see again!
    • kcap122, on 10/09/2008, -0/+1Not at all, I'm aware of one major pharmaceutical company in particular which has been investigating this avenue of pain treatment for the last 2-3 years. Expect to see a product within the next 7 years.
  • Hiltonizer, on 10/09/2008, -4/+43 handles of bourbon?

    makes going to work hurt less for me... lasts a whole week.
  • Link459, on 10/09/2008, -1/+4So.... they made super heroin?
    SWEET!
  • briansearles, on 10/09/2008, -1/+7Great! I get kidney stones every so often (genetics ftl) and sometimes even morphine can't help.
  • kidjay, on 10/09/2008, -3/+5DO NOT WANT.
  • isuisorisuaint, on 10/09/2008, -3/+2i can has no pain for 3 days
  • bewnshine, on 10/09/2008, -2/+10Why is there a picture of the stock market?

    Oh.
  • JDLamb88, on 10/09/2008, -0/+6There are many drugs that are stronger than morphine...
    • bipolarruledout, on 10/09/2008, -0/+1MUCH stronger than morphine. Check out the fentanyls.
    • DHTamus, on 10/09/2008, -0/+1Fentanyl doesn't have even close to the active life of this proposed treatment. Plus, these proteins are devoid of psychotropic effects, e.g. not rapidly spawning a new subset of junkies and addiction-justifying excuses.

  • StevesJobs, on 10/09/2008, -0/+6This is so digg
  • thomas040, on 10/09/2008, -4/+2where do I sign up? My ass is killing me!
    • ZBeeblebrox, on 10/09/2008, -1/+0Lubrication my friend, lubrication.
  • chickenloco, on 10/09/2008, -2/+1No more morphine? WHAT?
  • ArmchairEcon, on 10/09/2008, -1/+6They already have something that is 8x the strength of morphine..its called hydromorphone (dilaudid)... also a narcotic.. as well as other narcotics that can usually be described in terms of multiples of morphine in terms of efficacy. (someone mentioned fantanyl is something like 70x the efficacy of morphine)
    • elie195, on 10/09/2008, -1/+2sooooooooooooo good...almost as good as oxycodone....

      oh, those were the days... *sniff*
    • secrity, on 10/09/2008, -0/+1This is longer lasting and doesn't appear to be a narcotic. It probably has fewer side effects. They may also be able to increase the efficacy of this drug.
    • newms32, on 10/09/2008, -0/+1The whole point of this is to make a painkiller that doesn't have the side effects that all current opioids have, including hydromorphone. Potency isn't a motivating factor at all, we already have etorphine (elephant tranquillizer) which is roughly 10,000x the potency of morphine. You need to adjust the dose before any opioid is taken; one that's 8x as potent will need to be given at 1/8th the dose to avoid overdose.
  • thomas040, on 10/09/2008, -7/+3where do I sign up? My ass is killing me!
  • AboveandBeyond, on 10/09/2008, -1/+7Fentanyl has been there for ages.
    http://en.wikipedia.org/wiki/Fentanyl

    and
    Carfentanil
    http://en.wikipedia.org/wiki/Carfentanil
    It has a quantitative potency approximately 10,000 times that of morphine and 100 times that of fentanyl
    • secrity, on 10/09/2008, -0/+2This new medication appears to have far fewer side effects. It is also not a narcotic and has a much longer duration.
  • theetoecutter, on 10/09/2008, -0/+1"Pain dont hurt ! "
  • OffPiste, on 10/09/2008, -4/+2A whole bunch of Rethuglicans will be happy that they have this new drug after Obama takes their money and gives it to the people that really deserve it.
  • eers2snow, on 10/09/2008, -0/+3I want to party with these guys!!!!
  • fenderjazz, on 10/09/2008, -0/+5Can they come up with a new name first? Personally, I don't want to get a PAP injection the same day my girlfriend gets a pap smear...
  • SIN002, on 10/09/2008, -1/+1Can't wait to kill myself! :)
  • rowlodge, on 10/09/2008, -1/+1if it leaves the high off and just makes you feel numb that would make it less desirable to a junkie trying to sell it as a stimulant.
    • secrity, on 10/09/2008, -0/+3Most pain killers that I know of are not stimulants.
  • PGPirate, on 10/09/2008, -0/+5Hey Guys, wanna get hiiigh?

    http://imagecache2.allposters.com/images/pic/HPM/S ...
  • joels2, on 10/09/2008, -1/+1Details at http://www.neuron.org/content/article/abstract?uid ...
  • maleficdog, on 10/09/2008, -2/+0Dr Greg House is calling, and apparently he'll kill us all if we dont send him over a sample right now
  • siwasher, on 10/09/2008, -0/+2It says "8 times stronger" in the headline, but not in the article. In the article, it says "suppressed pain as effectively as morphine but for substantially longer." "As effectively" doesn't sound like "8 times stronger" to me.
    • newms32, on 10/09/2008, -0/+0Potency refers to the dose that's needed and is mostly irrelevant. 8x the potency doesn't mean 8x as effective, it just means you need to take 1/8th the dose.
  • Mohdoo, on 10/09/2008, -0/+7Wish I had this when I had my dick operated on.
  • opiv421, on 10/09/2008, -0/+4DO WANT.
  • spyd3rweb, on 10/09/2008, -0/+1Does it make you Comfortably Numb?
  • Hyperion1144, on 10/09/2008, -0/+4Now only 12 short years of clinical trials before it comes to market. Where we will find out 4 years later that the 12 years of clinical trials were conducted by researchers who were being bought off by the company who designed this drug so we would not find out that in fact this stuff causes some horrifying and permanent damage to the patients who take it.
    • Stroggoth, on 10/09/2008, -0/+1Like cipro and levaquin. Two drugs that ***** you up for years, and doctors hand them out to anyone with a cough. These painkillers can't be much worse, if at all.
  • somepuertorican, on 10/09/2008, -1/+2...Or I could just smoke this marijuana. Mmmmm.
  • mydjtl, on 10/09/2008, -0/+6stronger is a misnomer... you cant even measure the strength of a painkiller.. all you can measure is its potency and efficacy...

    http://en.wikipedia.org/wiki/Potency_(pharmacology ...
    • Paulish, on 10/09/2008, -0/+1I bet my pain killer can bench more than yours.
    • newms32, on 10/09/2008, -0/+0You're right in that "stronger" is being used in the wrong way, but there's more to painkillers than potency and efficacy. Analgesic effect and the therapeutic ratio are what determines a painkiller's real worth, as they describe how well it can reduce pain and how much pain can be reduced before harmful side effects kick in.
      http://en.wikipedia.org/wiki/Therapeutic_ratio
  • SeraphIXI, on 10/09/2008, -0/+5wiki: "Prostatic acid phosphatase is present in semen..."
    So, next time your gf has a headache.. you know
    I'm just sayin.
    • Hyperion1144, on 10/09/2008, -0/+1Dually noted.... ;)
    • bobfell, on 10/09/2008, -0/+1PAP levels are an indicator for prostate cancer so if you are curing your gf headaches, you better be going to the doctor.
  • AzzX, on 10/09/2008, -0/+1What sort of pain does morphine not take care off?
    • useraccess, on 10/09/2008, -0/+2There are some with such intense pain that morphine can't put a dent in it. I know someone dealing with bone necrosis caused by prolonged use of steroids to treat transplant rejection. She deals with major pain over a prolonged period of time. This would be perfect for her. Fentanyl and morphine don't touch the pain. Morphine based drugs also become less effective over time requiring increased dosages. This new drug could have strong potential among many with intolerable chronic pain.
    • Woknblues, on 10/14/2008, -0/+1Morphine depresses the respiratory function. Not always a good thing.
  • coastiefish, on 10/09/2008, -0/+0OTC! FTW!
  • kpwells, on 10/09/2008, -0/+2Dugg ✔
  • L4mb, on 10/09/2008, -0/+3Can't wait to abuse the ***** out of that.
  • filovirus, on 10/09/2008, -0/+2Dilaudid 1 MG is equipotent to Morphine 8-10 MG

    Dilaudid, the new Demerol
    • kelsosmythe, on 10/09/2008, -0/+1Yeah... I was getting 4MG IV every 4 hours after my last surgery.

      That ***** doesn't ***** around.
  • TheCollective00, on 10/09/2008, -1/+1"The study published in the journal Neuron involved injecting the protein prostatic acid phosphatase (PAP) into the spines of genetically modified mice who were in serious pain."

    Kinda makes you wonder how the scientists caused the mice such pain, doesn't it?
    • newms32, on 10/09/2008, -0/+11. Hot plate test - set the mouse on a hot plate and time how long it takes to lift their paws and lick them, which is the normal response to heat (a few seconds)
      2. Tail flick assay - dip the tail in water that's borderline hot-to-the-touch and time how long it takes them to flick their tail out (again a few seconds)
      3. Acetic acid test - inject dilute acetic acid (vinegar) into the intestines and judge analgesia based on behavioral response

      There are some variations but those are the most common. Before everyone rushes in to denounce the cruelty, the tests are limited to certain time frames to prevent tissue damage from occuring. If the analgesic is so powerful that the mouse won't remove its tail from the water at all, the test is stopped well before damage would occur.

      So yeah, they're in pain, but it's not Guantanamo Bay or anything.
      • TheCollective00, on 10/09/2008, -0/+0I can accept this. Thanks for putting my conscience at ease.
      • Stroggoth, on 10/09/2008, -0/+0>conscience

        I want con-science too!
  • morepowerr, on 10/09/2008, -2/+1So now all we need is some nut job too pump hem self full of this. The go out and start wasting people. Now the cop will have to cup off his head to stop him.
    • mockupscaledown, on 10/09/2008, -0/+3Umm, have you ever taken a pain killer before? Or an introductory English class?
  • atact88, on 10/09/2008, -0/+2Oh boy, here we go.
    "My drugs are too expensive! I use a 30 day supply in 18 days! Bail us out, Federal government!"
  • purpleerckleman, on 10/09/2008, -1/+1damn crazy
    more ways to ease people pain
    i like it but cmon
    once consumers get a hold of it
    there going to want it more
    morphene is already addicting just like oxycotton
    • rakaur, on 10/10/2008, -0/+1Are you a retard?

      Oxycodone (the active ingredient in OxyContin) is about equal to morphine in terms of potency. There is a difference between dependency and addiction.

      Also, the whole point of this article is that it provides pain relief on a higher scale than morphine and it's *not a narcotic*.
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